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Aurélie HOUEL
Directeur Assurance Qualité / Responsable Affaires Réglementaires Sécurité Produits chez SEPPIM SAS
September 2015
Autoclave with no drying cycle – what is the consequence on sterilization state during the storage?
< 1 min reading time

Hi,
I hope to have some help on sterilization process with an autoclave which has no drying cycle.
We use this autoclave to improve the state of cleanliness of our material used during the manufacturing process. We want to change this process, but I need to have more data on the sterilization state of wet material.
What is the consequence of the humidity on the sterilization state? Is there a risk of contamination of the material during the storage if the humidity is not suppress after autoclaving cycle?

source: https://www.linkedin.com/groups/78665/78665-6051350295148052484

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Posted by Aurélie HOUEL
Asked on September 20, 2015 12:00 am
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Karen Boyd, ASQ CQA The consequences of autoclaving without a drying cycle could be hazardous; rust, mold, not to mention most likely against device manufacturer's reprocessing validations and recommendations (IFU's) as drying methods are inclusive / critical to safe and proper sterilization. Generally, instruments should be cool and dry prior to storage after autoclave.
If you are the device manufacturer, ensure any process changes are properly validated before enacting changes. Whether the devices will undergo an automated dry cycle or manually dried, drying must be part of the finished sterilization process, prior to storage of sterile devices.
Cleanliness is different from sterilization. Devices can be clean, by physical appearance, but not necessarily sterile or void from contaminants. Do your research or enlist the help of a subject matter expert or lab for this project.
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I agree with Karen, no drying either as a design flaw or operational error is responsible for a huge number of the positive biologicals we investigate. It is essential.
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Stuart Briefer without proper drying after autoclave sterilization, residual amounts of blood will turn the appliance red/rusty color that cannot be removed later. other bodily fluids not properly removed, cleaned, autoclaved and dried will lead to instrument deterioration
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Karen Boyd, ASQ CQA If proper cleaning and sterilization methods are utilized, you would not / should not have any residual bodily fluids or blood on devices! Drying is to prevent instrument deterioration via the material composition of the device and trapped water / steam. Drying does not and cannot remove contaminants / pathogens. Rust (iron oxide) can develop on any metal instruments not properly dried, even stainless steel.
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Tom Nonnemaker Thank you clarifying Karen. Above response was a bit misleading.
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Karen Boyd, ASQ CQA Happy to help where I can.
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Stuart Briefer Thank you too for explaining that to me. I was misled by the rep
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Karen Boyd, ASQ CQA (Side note: If dried blood or foreign material is identified on instruments post-sterilization, those instruments should be handled with caution, deemed contaminated, and quarantined for decontamination.)
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no drying = no sterile goods. Simple.
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Annika Fahlén Where you find water you will find life.. You need drying cycles!
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